Endogenous peroxidase enzymes are found in which cells/tissues?

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Multiple Choice

Endogenous peroxidase enzymes are found in which cells/tissues?

Explanation:
Endogenous peroxidase activity comes from enzymes already present inside certain cells, most notably myeloperoxidase in leukocytes. This means blood cells are a primary source of endogenous peroxidase in tissue sections, which is why blocking this activity is a standard step before HRP-based detection to prevent unwanted background staining. Neurons, adipocytes, and keratinocytes do not have significant endogenous peroxidase activity, so they contribute little to background. Therefore, blood cells are the correct source of endogenous peroxidase in this context.

Endogenous peroxidase activity comes from enzymes already present inside certain cells, most notably myeloperoxidase in leukocytes. This means blood cells are a primary source of endogenous peroxidase in tissue sections, which is why blocking this activity is a standard step before HRP-based detection to prevent unwanted background staining. Neurons, adipocytes, and keratinocytes do not have significant endogenous peroxidase activity, so they contribute little to background. Therefore, blood cells are the correct source of endogenous peroxidase in this context.

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