Which of the following is a B-cell marker?

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Multiple Choice

Which of the following is a B-cell marker?

Explanation:
B cells have a characteristic surface protein profile, and among the options, CD19 is the marker tied to the B-cell lineage. CD3 marks T cells, CD56 is associated with NK cells (and some T cells), and CD34 marks hematopoietic progenitors and endothelium. CD19 is expressed from early B-cell development through most mature B cells, making it a reliable indicator of B-cell populations in tissues and in lymphoma classification. (Plasma cells may downregulate CD19, but overall CD19 best identifies B cells among these choices.)

B cells have a characteristic surface protein profile, and among the options, CD19 is the marker tied to the B-cell lineage. CD3 marks T cells, CD56 is associated with NK cells (and some T cells), and CD34 marks hematopoietic progenitors and endothelium. CD19 is expressed from early B-cell development through most mature B cells, making it a reliable indicator of B-cell populations in tissues and in lymphoma classification. (Plasma cells may downregulate CD19, but overall CD19 best identifies B cells among these choices.)

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